Colistin-heteroresistance in carbapenemase-producing Enterobacter species causing hospital-acquired infections among Egyptian patients
نویسندگان
چکیده
منابع مشابه
Colistin heteroresistance in carbapenemase-producing Klebsiella pneumoniae.
Sir, Klebsiella pneumoniae is an important pathogen that causes severe and life-threatening infections. Most isolates demonstrate resistance to various antimicrobial agents. Carbapenems have been widely used to treat serious infections with multidrug-resistant K. pneumoniae. However, the increasing use of these compounds has led to the emergence of carbapenem-resistant isolates via acquired gen...
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The epidemiological characteristics of nosocomial infections among patients requiring chronic hemodialysis, a high-risk and rapidly growing population, have not been fully elucidated. During a 30-month cohort study, rates of bloodstream infections (BSIs), urinary tract infections (UTIs), pneumonia, and diarrhea caused by Clostridium difficile and the distribution of pathogens among hospitalized...
متن کاملNational survey of colistin resistance among carbapenemase-producing Enterobacteriaceae and outbreak caused by colistin-resistant OXA-48-producing
A Jayol 1 , L Poirel 1 , L Dortet 2 3 4 , P Nordmann 1 2 5 1. Emerging Antibiotic Resistance Unit, Medical and Molecular Microbiology, Department of Medicine, University of Fribourg, Fribourg, Switzerland 2. Associated National Reference Centre for Antibiotic Resistance, Le Kremlin-Bicêtre, France 3. Faculty of Medicine, South-Paris University, Le Kremlin-Bicêtre, France 4. Bacteriology-Hygiene...
متن کاملFRI-2 carbapenemase-producing Enterobacter cloacae complex in the UK.
Objectives Detection of rarer carbapenemases is challenging, as it requires molecular assays with comprehensive coverage or the use of phenotypic methods for the detection of carbapenemase activity. We describe a new class A carbapenemase, FRI-2, in an Enterobacter cloacae complex isolate following implementation of an in-house multiplex PCR for the detection of 'rare' class A carbapenemases. ...
متن کاملColistin heteroresistance in Enterobacter cloacae is associated with cross-resistance to the host antimicrobial lysozyme.
Here, we describe the first identification of colistin-heteroresistant Enterobacter cloacae in the United States. Treatment of this isolate with colistin increased the frequency of the resistant subpopulation and induced cross-resistance to the host antimicrobial lysozyme. This is the first description of heteroresistance conferring cross-resistance to a host antimicrobial and suggests that cli...
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ژورنال
عنوان ژورنال: Journal of Global Antimicrobial Resistance
سال: 2021
ISSN: 2213-7165
DOI: 10.1016/j.jgar.2020.11.019